Potion Explosion: The Fifth Ingredient

Yes. You may treat a Wild Ingredient as any color at any point, including placing it in any hole on a Potion; discard it into the Dispenser when the Potion is completed. (p. 2)

Take 1 Wild Ingredient marble from the Cauldron, if available, and put the marble you’re exchanging in its place; if no Wild Ingredients remain, take any marble from the Cauldron instead. Each exchange earns you 1 Reward token. (p. 2)

Yes: each Reward token is worth 1 point, while each Scolding token costs you 1 point. (p. 2)

Choose 1 Professor tile at the start of the game, either randomly or deliberately; its effect lasts for the whole game. The rules recommend using only 1 for your first few games, though experienced players can use 2 at once. (p. 3)

Yes. When choosing the 6 Potions for the game, freely mix the 8 base-game Potions and the 4 expansion Potions, then return the unused ones to their boxes and continue with the usual setup. (p. 4)

At the beginning of the game, place the Cauldron in front of the Dispenser where everyone can reach it, and put all Wild Ingredient marbles on its holes. (p. 2)